Improving Ultrasound B-Mode Image Quality with Coherent Plane-Wave Compounding Using Adaptive Beamformers Based on Minimum Variance


5.1. The Geometric Distortion

The values of the FWHM on the lateral and axial axes are shown in Table 1 for the regions F1, F2, and F3, and Figure 4 shows the graph with the average values of the FWHMAx and FWHMLat.
Figure 5a–i presents the beamformer simulation response for evaluating distortion in the methods: (a) DAS, (b) GSC, (c) EGSC, (d) EGSCL, (e) EGSC with the filter enhanced Lee (EGSCLe), (f) EGSCK, (g) EGSC with the filter enhanced Kuan (EGSCKe), (h) EGSCW, and (i) EGSC with the filter enhanced Wiener (EGSCWe).
We have noticed that, in the axial axis, the techniques presented relatively closer values of the FWHM, which means that there is no evident geometric distortion, as seen in Figure 5. In the lateral axis, more distortions occur, especially in the DAS method.

The EGSCW, EGSCWe, EGSCLe, and EGSCK equally decrease the average FWHMLat, obtaining a reduction of 0.46 mm (63%), compared to the DAS method, with 0.10 mm (27%) and 0.09 mm (25%) compared to EGSC and GSC techniques, respectively.

The EGSCKe presented the result closest to the actual value, representing a reduction in the average FWHMLat of 0.49 mm (67%), 0.13 mm (35%), and 0.12 mm (33%) compared to DAS, EGSC, and GSC techniques, respectively.

5.2. Contrast

The values of CR are shown in Table 2 for the regions CR1, CR2, and CR3, and Figure 6 shows the graph with the average contrast for each method. The values in Figure 6 show that all the methods combined with the Wiener filter obtained better contrast values than the other techniques.
Figure 7a–i shows the displayed images for simulation of contrast for the methods: (a) DAS, (b) GSC, (c) EGSC, (d) EGSCL, (e) EGSCLe, (f) EGSCK, (g) EGSCKe, (h) EGSCW, and (i) EGSCWe.

The EGSCWe technique generated a contrast mean value of 52.49 dB, representing an average contrast improvement of 19.66 dB (60%), 19.86 dB (61%), and 22.28 dB (74%) compared to EGSC, GSC, and DAS, respectively. We noticed that the EGSCWe improved the performance of the EGSCW contrast by 1.19 dB, approximately 2.3%.

The EGSCL shows a contrast value close to GSC and EGSC methods and presents an improvement of contrast of 2.35 dB (7.8%) with regard to the DAS technique. However, the EGSCLe decreased the contrast by 3.85 dB (11.7%), 3.65 dB (11.2%), and 1.23 dB (4%) compared to EGSC, GSC, and DAS, respectively.

The EGSCK technique presents the worst contrast value on average, with a reduction of 8.65 dB (26.3%), 8.45 dB (26%), and 6.03 dB (20%) compared to the EGSC, GSC, and DAS, respectively. Also, the EGSCKe shows a slight contrast improvement of 1.1 dB (3.6%) compared to the DAS method.

Regions close to the contour of the fetal phantom face were analyzed, the average contrast for each method is presented in the graph of Figure 8 and Figure 9a–i shows the images displayed for simulation in fetal phantom for the methods: (a) DAS, (b) GSC, (c) EGSC, (d) EGSCL, (e) EGSCLe, (f) EGSCK, (g) EGSCKe, (h) EGSCW, and (i) EGSCWe.

The EGSCW and EGSCWe methods obtained a reduction in the noise around the fetus, providing better visualization of the contour.

Numerically, the contrast value increased with these techniques compared to the others. These methods showed improvement of 3.59 dB (9%) and 4.02 dB (10%), respectively, compared to the DAS method. An improvement, in contrast, allows better visualization of different areas, densities, and contours, being a positive result.

The comparison between the simulation and in situ experimental results reveals strong consistency, in terms of contrast. While simulations provide valuable theoretical data, the in situ experiments confirmed the effectiveness of techniques such as the EGSCWe and EGSCW, which improved image quality in both simulations and practical conditions. The ability to achieve similar improvements in both domains suggests that these methods are robust, highlighting the potential applicability of these methods in real clinical scenarios.

The geometric distortion results with the EGSCL and EGSCLe methods presented an improvement in the FWHM for the simulation and phantom, compared to EBGSC, GSC, and DAS. In the contrast results, for simulation and phantom images, the regions closest to the transducer suffer a slight homogenization due to filtering, which decreases contrast, especially for the EGSCLe. However, EGSCL and EGSCLe generally presented values around the MVGSC and EGSC methods, indicating future research with these filters.

The EGSCK and EGSCKe methods showed excellent FWHM reductions for simulation and phantom data compared to the DAS, MVGSC, EGSC, EGSCL, and EGSCLe methods. However, in terms of contrast, the EGSCKe method presented values close to the DAS, and the EGSCK presented a significant decrease with the lowest contrast values, which may indicate that there are better techniques to improve this parameter.

In research presented by Tasnim et al. [18], the Kuan and Lee filters were applied in post-processing B-Mode ultrasound images of different areas: kidney, fetus, cyst, and liver. Analyzing other measures, including signal-to-noise ratio (SNR), it was possible to verify that these filters improved or worsened the image depending on the area of the body analyzed, compared to basic methods such as the median filter.
Wu et al. [17] also used the Lee filter in kidney and liver images, and the Lee filter allowed an increase in the SNR compared to the median filtering technique. This shows us that the results depend on the methods and regions applied, indicating further research with the Lee and Kuan filters.
Aliabadi et al. [11], evaluating the ESBMV method with Wiener filter (ESBMVW) and improved Wiener filter (ESBMVWe), achieved CR increments of 46.3 dB (133%) and 26.1 dB (129%) for the ESBMVW, and 52.5 dB (164%) and 32.3 dB (160%), for the ESBMVWe, in comparison with to the DAS and MV techniques, respectively. The research was carried out with values of L = 48, a center frequency of 5 MHz, and a transducer with 128 elements.
Another research study using the ESBMVW, by Zhao et al. [31], evaluating targets of 0.1 mm in diameter, obtained significant FWHM reductions of 0.02 mm (50%) and 0.42 mm (95%) compared to the MV and DAS method. Evaluating the CR using the ESBMVW beamformer presented the same positive characteristic, generating improvements of 27.44 dB (239%) and 25.69 dB (194%) concerning the DAS and MV.

Compared to conventional methods, the improvement in contrast and reduction in distortion could represent better visualization of tissues, detection of small targets, and greater detail of the areas analyzed, which is positive for clinical use, helping with the quality of B-mode images and also in imaging modes that require high framerate, such as elastography, ultrafast Doppler, and ultrasound localization microscopy (ULM).

In ULM imaging, for example, which uses microbubbles to generate images of microvessels, high framerates are required to create images. However, there are limitations in spatial resolution due to the point spread functions (PSFs) of multiple microbubbles, which, despite developments in recent years, still makes obtaining high-quality images a challenge [32,33,34]. Thus, techniques such as those proposed in this work that reduce lateral distortion could improve spatial resolution, enabling the reduction in errors and time in detecting microbubbles, consequently, generating better images of small vessels.

The sizes of the signal subspace functions in the beamformer eigenspace and the windows for the adaptive filters can present different contrast and lateral distortion results, which can help analyze different regions and need to be better studied.

In this work, we did not do tests with 3D Ultrafast images. However, as the filtering techniques improved the resolution, they can be applied to each processed frame before reconstructing the high-resolution 3D images.

The results obtained in this work, along with those reported in [11,17,18,31], underscore the effectiveness of the EGSCW and EGSCWe methods in enhancing the contrast ratio and spatial resolution of ultrasound images. These findings highlight the potential for further research into these methods.



Source link

Larissa C. Neves www.mdpi.com