JCM, Vol. 15, Pages 1059: The Role of Biodegradable Temporizing Matrix in Hand Surgery for Paediatric Recessive Dystrophic Epidermolysis Bullosa

Journal of Clinical Medicine doi: 10.3390/jcm15031059

Authors:
Aikaterini Bini
Michael Ndukwe
Greta Piccioli
Christina Lipede
Andrea Jester

Background/Objectives: The purpose of this study is to review the use of Biodegradable Temporizing Matrix (BTM) for releasing finger webspaces and flexion contractures in recessive dystrophic epidermolysis bullosa (RDEB) in paediatric patients and evaluate the short-term and mid-term results. Methods: Patients who underwent release of webspace fusion and flexion contractures followed by BTM application during the last two years (2022–2024) were included. The data collected included the patient demographics, previous surgical management, type of release, post-operative complications and final outcomes. BTM was used in four patients. Results: The functional outcomes were acceptable but temporary, as three cases required or are planned for re-operation due to recurrence. Conclusion: The surgical experience using BTM as a single-stage dressing/dermal substitute in hand surgery for paediatric RDEB has shown feasibility and safety regarding infection rates. To the best of our knowledge, this is the first reported study regarding the BTM use for releasing hands in epidermolysis bullosa.

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Aikaterini Bini www.mdpi.com