Molbank, Vol. 2026, Article M2141: (E)-Methyl 3-(2-amino-4-chloro-6-morpholinopyrimidin-5-yl)acrylate

Molbank doi: 10.3390/M2141

Authors:
Jorge Trilleras
Efraín Polo-Cuadrado
Jairo Quiroga

The synthesis of methyl (E)-3-(2-amino-4-chloro-6-morpholinopyrimidin-5-yl)acrylate 3 was accomplished using a Schlosser-modified Wittig reaction. Complete 1H and 13C NMR signal assignments confirm the formation of E-alkene.

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Jorge Trilleras www.mdpi.com